Tuesday, 25th June 2024 Computationally modelling the effects of transcutaneous tibial nerve stimulation Abstract: Transcutaneous tibial nerve stimulation (TTNS) is an established medical intervention for the treatment of disorders of incontinence. Based upon the principle of neuromodulation, this non-invasive technique is believed to alter bladder function via specific action on afferent sensory neurons. Though the technique is well established, and used in specialist NHS clinics, there remain a number of unknowns surrounding it’s exact neurobiological mechanism. In this talk, I will explain how computational modelling can allow us to simulate the network level effects of TTNS on the bladder control circuit, and that through doing so it is possible to construct a framework that allows the exploration of dose-related effects of the intervention. The talk will conclude with research indicating that through modifying the dose of the intervention it may be possible to treat seemingly opposing conditions. Event type: Workshop Date: Tuesday, 25th June Time: 11:00 Location: G.03 Speaker(s): Aidan McConnell-Trevillion, Chair/Host: Vaidotas Simkus This article was published on 2024-11-22
