Meet our 2019 CDT cohort. Emanuela MolinariPhD project: Health, mental health, social and economic outcomes in survivors of childhood cancerSupervisors: Sarah Wild, Colin Mclean, and Peter Hall Based on the data of 235,435 survivors of cancer diagnosed when young, recent studies have shown a substantial 5-fold excess of death during adult life when compared to read more the expected survival from the general population (30% versus 6% death rate respectively). The second most common cause of the excess of number of deaths is caused by circulatory disease. Among studies on cancer diagnosed when young, none has looked at mental health long-term effects of survivors. Two UK-wide research priority setting projects overseen by the James Lind Alliance, defined in the top 10 UK priorities for cancer survivors, their families and their healthcare professionals. Almost half of them concerned the long-term effects of a cancer diagnosis and treatment at young age, the importance of finding a way to compare treatments on the late-effects and developing targeted follow-up care to prevent serious health consequences. The project responds to the increasing demand from government bodies, patients and carers on quantifying the impact of cancer survivorship, exploiting the NHS investment in electronic health data and the UK drive in developing machine learning (ML)-tools for the healthcare. We will analyse big data of cancer registries linked with routine NHS data and public sector data through the National Safe Haven analytic platform for anonymised extracts of data (electronic Data Research and Innovation Service - eDRIS). We will use standard statistical approach and ML tools for better prediction of cancer outcomes. This article was published on 2024-11-22
